| Primary Identifier | MGI:3701697 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Gck |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| description | On congenic B6 background, analysis is done on mice with allele with pgk-neo selection cassette deleted through mating to cre transgenic mice; on the coisogenic 129S6 background, allele retaining pgk-neo is analyzed, and authors state that presence of neo has no apparent effect on phenotype compared with mice on C57BL/6J congenic background. MMRRC has 129S6 mice carrying Gcktm2Mgn (retaining neo cassette). |
| molecularNote | A construct with an inactivating single base pair mutation was introduced into exon 9 via site specific mutagenesis. This is predicted to to change amino acid 414 from lysine to glutamic acid in the encoded protein. |
