| Primary Identifier | MGI:3700739 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(TcraY1,TcrbY1)416Tev |
| Strain of Origin | (C57BL/6J x DBA/2J)F1/J | Is Recombinase | false |
| Is Wild Type | false |
| description | Transgenic mouse lines were derived from 2 transgene-expressing founder mice and designated lines 416 and 422. The Tg insert of line 416 was backcrossed onto C57BL/6 to create a congenic strain for use in experiments. |
| molecularNote | Single-cell embryos were coinjected with T-cell receptor alpha and T-cell receptor beta expression vectors containing the rearranged genomic Tcra and Tcrb VJ/V(D)J segments from the cytotoxic T-lymphocyte clone Y-1, which expresses a T cell receptor specific for the H2-Db-restricted SV40 large tumor antigen epitope I (amino acids 206-215). |
