| Primary Identifier | MGI:3701662 | Allele Type | QTL |
| Gene | Sle21 | Inheritance Mode | Dominant |
| Strain of Origin | 129P2/Ola | Is Recombinase | false |
| Is Wild Type | false |
| description | Sle21 and Sle18 interact. F2 animals with at least one 129-derived allele at Sle16 and homozygous for C57BL/6-derived alleles at Sle18 display significantly greater ANA compared to other F2 genotypes. |
| molecularNote | This allele confers susceptibility to systemic lupus erythematosus traits compared to C57BL/6. |