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Allele : Sle21<129P2/Ola> systematic lupus erythematosus susceptibility 21; 129P2/Ola

Primary Identifier  MGI:3701662 Allele Type  QTL
Gene  Sle21 Inheritance Mode  Dominant
Strain of Origin  129P2/Ola Is Recombinase  false
Is Wild Type  false
description  Sle21 and Sle18 interact. F2 animals with at least one 129-derived allele at Sle16 and homozygous for C57BL/6-derived alleles at Sle18 display significantly greater ANA compared to other F2 genotypes.
molecularNote  This allele confers susceptibility to systemic lupus erythematosus traits compared to C57BL/6.
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele