| Primary Identifier | MGI:3701764 | Allele Type | Targeted |
| Gene | Gck | Transmission | Germline |
| Strain of Origin | 129S6/SvEvTac | Is Recombinase | false |
| Is Wild Type | false |
| description | On congenic B6 background, analysis is done on mice with allele with pgk-neo selection cassette deleted through mating to cre transgenic mice; on the coisogenic 129S6 background, allele retaining pgk-neo is analyzed, and authors state that presence of neo has no apparent effect on phenotype compared with mice on C57BL/6J congenic background. MMRRC has B6 congenic mice carrying Gcktm3Mgn allele (with neo deleted.) |
| molecularNote | ES cells were modified using a construct with an activating single base mutation introduced into exon 10 via site specific mutagenesis to change amino acid 456 from alanine to valine. |
