| Primary Identifier | MGI:3701617 | Allele Type | Transgenic |
| Attribute String | Recombinase | Gene | Tg(Emx1-cre)1Ito |
| Strain of Origin | C57BL/6 | Is Recombinase | true |
| Is Wild Type | false |
| description | Adult expression of this transgene is seen in the olfactory bulb, neocortex, piriform cortex, hippocampus and amygdala of the brain. At 7-8 days of age expression is also observed in the inferior colliculus. Activity is primarily in excitatory neurons and astrocytes. Little or no activity is seen in inhibitory neurons. |
| molecularNote | An Emx1 positive PAC clone frome the RPCI-21 PAC mouse genomic library (PAC-Emx1#1) was modified by the insertion of an NLS-Cre-poly(A) cassette into the NotI site by homologous recombination in bacteria. Two independent recombination events were identified. This transgenic line was generated from the PAC-Cre-A fragment and has 2-3 copies of the transgene. |
