Primary Identifier | MGI:3702441 | Allele Type | Transgenic |
Attribute String | Conditional ready, Inserted expressed sequence, Reporter | Gene | Tg(CAG-cat,-Notch1)1Ysa |
Strain of Origin | (C57BL/6 x C3H)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene carries the Notch1 intracellular domain downstream of a chicken beta-actin promoter (CAG promoter) and a floxed chloramphenicol acetyltransferase gene (cat, a stuffer sequence). Upon cre-mediated excision of the cat gene, the modified allele expresses Notch1 in tissues where Cre is expressed. |