| Primary Identifier | MGI:3702620 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Igk-Lta/Ltb)10Cys |
| Strain of Origin | (C57BL/6J x DBA/2J)F2 | Is Recombinase | false |
| Is Wild Type | false |
| description | Mice of this line are reported to be almost identical to mice of line 4 (Tg(Igk-Lta/Ltb)10Cys). |
| molecularNote | The mouse Lta gene was fused with the transmembrane domain of Ltb and inserted into a vector containing the mouse Ig kappa (Igk) promoter and enhancer elements. Mice generated have multiple copies of the transgene and express a membrane form of lymphotoxin alpha (LTa) under control of the kappa light chain enhancer and promoter. The LTa transgene is selectively expressed in B lymphocytes. |
