Primary Identifier | MGI:3704944 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Wwox |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 6kb section containing exons 2-4 was replaced by a lacZ/neo cassette with a mouse intronic sequence, a splice acceptor site, and an IRES site. Western blot analysis confirmed the absence of the 46KDa protein and a beta-galactosidase assay confirmed lacZ expression. |