Primary Identifier | MGI:3708170 | Allele Type | Targeted |
Gene | Tcrb | Transmission | Germline |
Strain of Origin | 129S4/SvJae | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The Vbeta13 gene segment with its endogenous promoter and recombination signal sequences and a floxed pgk-neomycin resistance cassette is inserted upstream of the D segment. Insertion was confirmed by Southern blot analysis of ES cells and by increased expression of Vbeta13 T cells in homozygous mice. |