| Primary Identifier | MGI:3706439 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Ins2-Nos2)40Okam |
| Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | false |
| Is Wild Type | false |
| description | J:116040 uses transgenic Nos2 mice with no identification of the line. The two lines created in J:45520 are similar, with line 40 having a more severe phenotype. Assumption was made that line 40 was used subsequently for this reason. rpb 05/01/2007 |
| molecularNote | The transgenic construct was composed of the rat insulin II promoter and the 3.5 kb cDNA fragment containing the entire mouse Nos2 gene coding region with the SV40 intron/polyadenylation signal ligated to it. Line 31 was subsequently established. Western blot analysis shows expression of Nos2 in pancreatic islets, but nowhere else. |
