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Allele : Tg(Camk2a-Bdnf)A9Stl transgene insertion A9, Susumu Tonegawa

Primary Identifier  MGI:3709467 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Camk2a-Bdnf)A9Stl
Strain of Origin  (C57BL/6 x DBA/2)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene construct has the rat Bdnf cDNA sequence, with a Kozak sequence inserted in front of the translation initiation site, controlled by the mouse Camk2a promoter. The SV40 intron/polyA sequence was inserted the 3' to the Bdnf cDNA. ISH demonstrated that Bdnf overexpression is mainly restricted to the forebrain regions, including all of the neocortex, parts of the hippocampus, amygdala and striatum.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

12 Publication categories

Trail: Allele