Primary Identifier | MGI:3709371 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Alb-F5)2Dgi |
Strain of Origin | (C57BL/6 x SJL)F1 or C57BL/6 x (C57BL/6 x SJL)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgenic construct has the mouse albumin promoter driving expression of the murine F5 (FV) gene including the entire coding sequence. An IRES-EGFP cassette with a bacterial gene wasinserting after the F5 coding sequence. A chimeric intron with optimized splice signals was introduced upstream of the F5 cDNA enhance gene expression. Transgenic F5 expression is restricted to the liver. EGFP expression is not detected. |