| Primary Identifier | MGI:3709380 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Pf4-F5)1Dgi |
| Strain of Origin | (C57BL/6 x SJL)F1 or C57BL/6 x (C57BL/6 x SJL)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgenic construct has the mouse Cxcl4 (Pf4, platelet factor 4) driving expression of the murine F5 (FV) gene including the entire coding sequence. An IRES-EGFP cassette with a bacterial gene was inserted after the F5 coding sequence. A chimeric intron with optimized splice signals was introduced upstream of the F5 cDNA enhance gene expression. Transgenic F5 expression is restricted to megakaryocyt-containing tissues (to spleen and bone marrow). EGFP expression is not detected. |
