| Primary Identifier | MGI:3709884 | Allele Type | Targeted |
| Attribute String | Not Specified | Gene | Cbl |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A Y737F substitution was introduced into the locus. The Y737F substitution (Y731F in the human CBL protein) ablates the binding site of the p85 subunit of PI 3-kinase to Cbl, as well as the Cbl-mediated activation of this lipid kinase in several cell types. |
