Primary Identifier | MGI:3712475 | Allele Type | QTL |
Gene | Vms1 | Strain of Origin | A/J |
Is Recombinase | false | Is Wild Type | false |
description | 71% of F2 animals homozygous for this allele exhibit myocarditis. |
molecularNote | This allele confers susceptibility to coxsackievirus B3-induced myocarditis compared to C57BL/10Snsg. This allele also confers susceptibility to coxsackievirus B3-induced sarcolemma damage in females compared to C57BL/10SnSg. |