| Primary Identifier | MGI:3711451 | Allele Type | Targeted |
| Attribute String | Hypomorph, Inducible, Recombinase | Gene | Runx1 |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Induced With | tamoxifen | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | A targeting vector was designed to insert a tamoxifen-inducible cre recombinase flanked by two mutated estrogen receptors and a floxed neo into the Runx1 gene downstream of the proximal (P2) promoter. The neo was subsequently removed via exogenous cre expression. A subsequent reference states that the allele was determined to be hypomorphic, with homozygotes developing to term but dying in the first postnatal day. |
