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Allele : Piwil4<tm1Ghan> piwi-like RNA-mediated gene silencing 4; targeted mutation 1, Gregory J Hannon

Primary Identifier  MGI:3712153 Allele Type  Targeted
Attribute String  Null/knockout Gene  Piwil4
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  A 10 kb vector including a PGK-puro, and a duplication of the genomic region encompassing exons 9-12 were inserted downstream of exon 12. This insertion was predicted to insert multiple in-frame stop codons and to produce a nonfunctional allele. RT-PCR confirmed the absence of transcript in mutants and is concluded to be either severely hypomorphic or a null allele.
  • mutations:
  • Insertion,
  • Duplication
  • synonyms:
  • Miwi2<->,
  • Miwi2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

1 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

20 Publication categories

Trail: Allele