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Allele : Prex1<tm1Hcew> phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1; targeted mutation 1, Heidi C E Welch

Primary Identifier  MGI:3716859 Allele Type  Targeted
Attribute String  Null/knockout Gene  Prex1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 5, which encodes catalytic residues in the DH domain, was replaced with a neomycin resistance cassette and a translational stop codon. Northern blot confirmed absence of transcript in mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • P-Rex1<->,
  • P-Rex1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

14 Publication categories

Trail: Allele