|  Help  |  About  |  Contact Us

Allele : Ar<tm1.1Jdz> androgen receptor; targeted mutation 1.1, Jeffrey D Zajac

Primary Identifier  MGI:3716756 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ar
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Cre-mediated recombination in the germline resulted in the loss of exon 3, which encodes the second zinc finger of the DNA-binding domain. This deletion has been designed to retain the normal reading frame so that the mutant AR can bind ligand but is unable to bind DNA and regulate target gene transcription.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • AR<deltaZF2>,
  • AR<deltaZF2>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

16 Publication categories

Trail: Allele