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Allele : Tg(Gfap-APOE_i4)50Hube transgene insertion 50, Gerda Huber
Primary Identifier  MGI:3717390 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Gfap-APOE_i4)50Hube
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  A cDNA encoding the human APOE isoform 4 was cloned into a vector downstream of the rat glial fibrillary acid protein (Gfap) promoter and regulatory elements and upstream of the human beta-globin splice and polyadenylation sites. The linearized construct was injected into the male pronuclei of B6D2F1 zygotes.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(Gfap-APOE*4)50Hube,
  • Tg(Gfap-APOE*4)50Hube,
  • ApoE4(C112R),
  • ApoE4(C112R),
  • AD71,
  • AD71
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories

Trail: Allele




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