| Primary Identifier | MGI:3715920 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Dvl2*K446M/EGFP)5Awb |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The Dvl2 promoter drives the expression of Dvl2 with EGFP fused downstream of the 15th exon with a LoxP site inserted 3' of Acadvl, and a point mutation introduced at the codon 446. This mutation is predicted to alter lysine 446 to methionine in the encoded protein. The point mutation is identical to a varaint identified in Drosophila that abolishes planar cell polarity function. |
