| Primary Identifier | MGI:3718034 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Cacna1a |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin resistance cassette flanked by loxP and lox71 was inserted into exon 1. A knock-in vector containing plox66-HS13NP was inserted along with a cre-expressing plasmid, resulting in the replacement of the neo with the vector. The vector contained lox66, IRES, human cDNA encoding the calcium channel, voltage-dependent, P/Q type, alpha 1A subunit gene from HS13NP (GenBank AB035727), a polyA signal and an FRT-flanked CAG-hygro gene. The human gene contained 13 polyglutamine repeats. |
