Primary Identifier | MGI:3721399 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Evc |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The first exon was replaced by a beta-galactosidase gene. LacZ recapitulates endogenous expression. No RNA or protein was detected by RT-PCR and immunofluorescent staining of the developing bones of homozygous mice. Expression of two proximal genes, Crmp1 and Evc2, were not affected. |