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Allele : Tg(Thy1-BACE1)16Vln transgene insertion 16, Fred Van Leuven
Primary Identifier  MGI:3722132 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Thy1-BACE1)16Vln
Strain of Origin  C57BL/6 and DBA Is Recombinase  false
Is Wild Type  false
molecularNote  A construct containing the human BACE1 cDNA inserted in the mouse Thy1 gene cassette in the pTSC plasmid was microinjected into day 0.5 pronuclear DBA/C57BL/6 embryos. 5 founders were generated and line 16 was found to have high human BACE1 expression by Western blot. Line 16 was established for further use and characterization.
  • mutations:
  • Insertion
  • synonyms:
  • BACE,
  • BACE
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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