| Primary Identifier | MGI:3757641 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Spr |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A portion of exon 1, intron 1 and all of exon 2 were replaced with a PGK-neo cassette. The absence of full length transcript was confirmed by northern blot. Exon 2 encodes a short chain dehydrogenase/reductase domain that is essential for Spr function and its deletion and resulting frameshift is expected to produce a null allele. |
