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Allele : Atf6<tm1.1Rjk> activating transcription factor 6; targeted mutation 1.1, Randal J Kaufman

Primary Identifier  MGI:3723526 Allele Type  Targeted
Attribute String  Null/knockout Gene  Atf6
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 4 was deleted by Cre-mediated recombination to create a truncated protein product of 72 amino acids that lacks any functional elements of the protein. This allele also contains an FRT flanked neo cassette upstream of the deleted exon 4. The absence of protein was confirmed by western blot analysis on mouse embryonic fibroblast cells. Removal of the neo cassette has no effect on the phenotype.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Atf6alpha<->,
  • Atf6alpha<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

18 Publication categories

Trail: Allele