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Allele : Tg(Camk2a-cre/ERT2)2Gsc transgene insertion 2, Gunther Schutz

Primary Identifier  MGI:3759305 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(Camk2a-cre/ERT2)2Gsc
Strain of Origin  FVB/N Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
description  Three lines were created (lines 1, 2 and 3) with 1, 2 and 4 copy numbers of the transgene, respectively. Line 2 was choosen as the representative line because while copy number affects the level of expression similar phenotypes are produced and the majority of the reporting in J:125230 focuses on line 2.
molecularNote  The Camk2a promoter was used to drive expression of a cre and human estrogen receptor fusion (cre/ESR1). Expression is inducible by tamoxifen and localizes to the neurons of the adult forebrain.
  • mutations:
  • Insertion
  • synonyms:
  • CaMKCreER<T2>,
  • Tg(Camk2a-cre/ESR1)2Gsc,
  • CaMKCreER<T2>,
  • Tg(Camk2a-cre/ESR1)2Gsc
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

1 Driven By

Trail: Allele

69 Publication categories

Trail: Allele