| Primary Identifier | MGI:3760085 | Allele Type | Targeted |
| Attribute String | Dominant negative, Hypomorph | Gene | Krt19 |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neo cassette was inserted into intron 6. In the wild-type allele this intron is always spliced out but in the mutated allele in some transcripts only part of intron 6 (between neo and exon 7) is spliced out, resulting in the expression of both wild-type and truncated protein product. Expression of the truncated and full length protein products was confirmed by western blot analysis on protein extracted from the epidermis. |