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Allele : Krt19<tm1Alki> keratin 19; targeted mutation 1, Abraham L Kierszenbaum

Primary Identifier  MGI:3760085 Allele Type  Targeted
Attribute String  Dominant negative, Hypomorph Gene  Krt19
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A neo cassette was inserted into intron 6. In the wild-type allele this intron is always spliced out but in the mutated allele in some transcripts only part of intron 6 (between neo and exon 7) is spliced out, resulting in the expression of both wild-type and truncated protein product. Expression of the truncated and full length protein products was confirmed by western blot analysis on protein extracted from the epidermis.
  • mutations:
  • Insertion
  • synonyms:
  • K9<neo>,
  • K9<neo>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele