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Allele : Tg(Tcra51-11.5,Tcrb51-11.5)AR206Ayr transgene insertion AR206, Alexander Y Rudensky
Primary Identifier  MGI:3760401 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Tcra51-11.5,Tcrb51-11.5)AR206Ayr
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Fragments of Valpha18 (P14A.1)-Jalpha45 and Vbeta6-Dbeta1-Jbeta2.2 were PCR-amplified from genomic DNA of hCLIP:I-Ab-specific T cell hybridoma 51-11.5 grown in H2b (C57BL/6J) mice. The amplified fragments were inserted into separate vectors and co-injected into (C57BL/6 x DBA/2)F2 embryos. Mouse -derived T cell receptor promoters (Tcra, Tcrb) drive expression. This founder line (AR206), carrying co-integrated transgenes, was backcrossed more than 15 times to C57BL/6.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(Tcra-V18-Tcra-J, Tcrb-V6-Tcrb-D-Tcrb-J)AR206Ayr,
  • TCli TCR,
  • TCli TCR,
  • Tg(Tcra-V18-Tcra-J, Tcrb-V6-Tcrb-D-Tcrb-J)AR206Ayr
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1 Feature

Trail: Allele

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2 Expresses

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0 Mutation Involves

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7 Publication categories

Trail: Allele




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