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Allele : Ptprb<tm1Dgen> protein tyrosine phosphatase receptor type B; targeted mutation 1, Deltagen

Primary Identifier  MGI:3760508 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Ptprb
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
Project Collection  Deltagen
molecularNote  An IRES-lacZ-PGK-neo cassette was inserted between exons 17 and 19 replacing exon 18 and its surrounding intronic sequences. Sequences encoding the first six transmembrain domains are replaced. The predicted protein is fused to a beta-galactosidase peptide and lacks the endogenous transmembrane and cytoplasmic domains. The absence of protein product was confirmed by western blot analysis on protein extracts from embryonic endothelioma cells established from E9.5 mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele