Primary Identifier | MGI:3761645 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(CD207-cre)1Dhka |
Strain of Origin | (C57BL/6J x SJL/J)F2 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A cre recombinase gene optimized for mammalian codon usage was inserted right after the ATG of exon 1 in a human BAC, which was then injected into oocytes. Insertion of the cre gene was confirmed by PCR on genomic DNA. Cre expression is restricted to all epidermis MHC-II+CD11c+ Langerhans cells but not other CD207 expressing cells. |