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Allele : Ptprb<tm1Gdy> protein tyrosine phosphatase receptor type B; targeted mutation 1, George D Yancopoulos
Primary Identifier  MGI:3763454 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Ptprb
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6NTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  An 11.8-kb segment of the gene extending from 27 nucleotides in exon 2 through exon 3 was replaced with a beta-gal reporter gene and a loxP-flanked neomycin selection cassette. Quantitative RT-PCR on 9.5 embryos demonstrated no gene expression in homozygotes. Beta-gal expression was observed in the developing cardiovascular system.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • VE-PTP<->,
  • VE-PTP<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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