| First Author | Keck J | Year | 2020 |
| Journal | Microbes Infect | Volume | 22 |
| Issue | 8 | Pages | 360-365 |
| PubMed ID | 32084556 | Mgi Jnum | J:321676 |
| Mgi Id | MGI:6881621 | Doi | 10.1016/j.micinf.2020.02.005 |
| Citation | Keck J, et al. (2020) The Role of MicroRNA-155 in Chlamydia muridarum Infected lungs. Microbes Infect 22(8):360-365 |
| abstractText | Our laboratory has investigated the role of an evolutionarily conserved RNA species called microRNAs (miRs) in regulation of anti-chlamydial protective immunity. MiRs including miR-155 expressed in specific immune effector cells are critical for antigen specific protective immunity and IFN-gamma production. Using miR-155 deficient mice, and a murine pulmonary model for chlamydial infection, we report here 1) the effect of host miR-155 on bacterial burden, and 2) identify probable immune genes regulated by miR-155. |
