| Primary Identifier | MGI:3764898 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Tert |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The gene locus contains 15 exons. A linearized targeting vector containing a neomycin cassette in the reverse orientation and exons 3-8 was used. After targeting, the allele contained a neomycin cassette in the reverse orientation after the endogenous exon 8, with exons 3-8 repeated downstream of the neo cassette. Insertion caused gene inactivation as determined by semi-quantitative RT-PCR on embryonic fibroblasts, liver, and testes. |
