Primary Identifier | MGI:3767329 | Allele Type | Targeted |
Gene | Ighg1 | Transmission | Germline |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The exons encoding the secretory form of human IGHG1 and a neo cassette with a 5' loxP site were inserted upstream of exon 1. An additional loxP site was inserted between the exons encoding the secretory and membrane form of the mouse gene. Cre-mediated recombination resulted in the removal of the neo cassette and the secreted mouse form. |