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Allele : Fasn<tm1.1Sem> fatty acid synthase; targeted mutation 1.1, Clay F Semenkovich

Primary Identifier  MGI:3765071 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fasn
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Mice carrying the Fasntm1Sem allele were crossed with Cre transgenic mice to remove exons 4-8 of the gene. Germline deletion of the exons was verified by PCR, and gene inactivation was demonstrated by a 50% reduction in enzyme activity in liver lysates from heterozygote.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • FAS-deficient,
  • FAS-deficient
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele