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Allele : Ltbp1<tm1Veto> latent transforming growth factor beta binding protein 1; targeted mutation 1, Vesna Todorovic

Primary Identifier  MGI:3765966 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ltbp1
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6NTac)F1
Is Recombinase  false Is Wild Type  false
description  Ltbp1tm1Veto and Ltbp1tm2Veto mice exhibit identical defects.
molecularNote  457 bp of the 3' portion of exon 1 and 209 bp of the downstream exon were deleted and replaced with a lacZ gene and neo cassette using Velocigene technology. The neo cassette was removed by cre-mediated recombination. The absence of protein was confirmed by western blot analysis on protein extracts from E14.5 hearts.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ltbp1L<->,
  • Ltbp1L<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele