Primary Identifier | MGI:3765977 | Allele Type | Targeted |
Gene | Scn5a | Transmission | Germline |
Strain of Origin | 129/SvEv | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A 9 bp deletion (deleting amino acids lysine, proline and glutamine; deltaKPQ) was introduced into exon 26. A floxed thymidine kinase and neo cassette was also inserted into intron 26 but was removed by cre-mediated recombination using a cre recombinase expressing vector. Modification to the transcript was confirmed by RT-PCR. |