| Primary Identifier | MGI:3768913 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Frs2 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Frs2tm1Fwan mice were crossed with Cre knockin mice to generate a null allele in the germline. A truncated gene transcript was confirmed by RNAse protection assay on heterozygote kidney extracts. Heterozygotes were indistinguishabe from wild-type mice, suggesting that the truncated transcript did not encode for a dominant-negative protein. |
