Primary Identifier | MGI:3769140 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Myh6-Myh7)102Rbns |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
description | 5 lines were created with between 1.7 and 3.3-fold overexpression. Line 102 was chosen as the representative line because it exhibits 83% ventricular replacement of Myh6 with Myh7. |
molecularNote | The expression of Myh7 is driven by the Myh6 promoter to accomplish replacement of myosin heavy chains in cardiac tissue. |