Primary Identifier | MGI:3769667 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Foxl1-cre)1Khk |
Strain of Origin | (C57BL/6 x SJL)F1 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | Using BAC RP23-446J14, the researchers replaced the Foxl1 open reading frame with an IRES-cre cassette and the Foxc2 gene with an frt-flanked kanamycin cassette to prevent any expression from it. The kanamycin was later removed by flp-mediated recombination. Cre is expressed in the mesenchymal cells of the stomach and intestines. |