| Primary Identifier | MGI:3769034 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Pold1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A nucleotide substitution in exon 15 resulted in the amino acid substitution of lysine for leucine at position 604 (L604K). This amino acid is located in a highly conserved motif A in the active site of the polymerase domain. An neo cassette was also inserted into intron 11. Expression was confirmed by western blot analysis on extracts from the liver. |
