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Allele : Cfp<tm1.1Song> complement factor properdin; targeted mutation 1.1, Wen-Chao Song

Primary Identifier  MGI:3771611 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Cfp
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was constructed where a loxP site was inserted upstream of exon 3, and a FRT flanked neomycin resistance cassette followed by a loxP site was inserted downstream of exon 5. Upon recombination, the neomycin cassette inserted in the intended location but the upstream loxP site failed to recombine. FLPe recombination removed the FRT-flanked neomycin cassette located in intron 5 and endogenous gene expression was restored.
  • mutations:
  • Insertion
  • synonyms:
  • properdin rescued knockout,
  • properdin rescued knockout,
  • fP<flox>,
  • fP<flox>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele