Primary Identifier | MGI:3772668 | Allele Type | Targeted |
Gene | Kcnq1ot1 | Transmission | Germline |
Strain of Origin | 129S4/SvJae | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A polyadenylation signal in the opposite orientation preceded by a floxed neo cassette was inserted downstream of the endogenous promoter. The neo cassette was removed by cre-mediated recombination. Expression upstream and downstream of the insertion was confirmed by RNase protection assay and RT-PCR. |