Primary Identifier | MGI:3769998 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(IGFBP1)2Miel |
Strain of Origin | C57BL and CBA | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The hIGFBP-1 transgene (isolated from a human cosmid clone) contains the entire structural IGFBP1 gene and all the cis acting sequences necessary to direct appropriate tissue-specific and regulated gene expression. Founder mice (line c1:2-2) were bred to CBA/Ca and the transgene copy number was found to be between 8 and 20. |