| Primary Identifier | MGI:3770248 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Ins2-Chrm3*)1Jwe |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| description | Two lines were created (1 and 2) with identical phenotypes. |
| molecularNote | The rat insulin 2 promoter was used to drive expression of the gene in beta cells. Chrm3 contains two modifications (an N-terminal 9 amino acid hemagglutinin epitope tag was added and a central portion of the third intracellular loop, Ala274 to Lys469, was deleted) that do not change its functionality but allow the researchers to distinguish it from the endogenous gene product. |
