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Allele : Pik3ca<tm2Bvan> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 2, Bart Vanhaesebroeck

Primary Identifier  MGI:3770257 Allele Type  Targeted
Attribute String  Reporter Gene  Pik3ca
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A point mutation was engineered into the locus, resulting in the DFG to AFG conversion in the conserved DFG motif at the C-terminal kinase domain. A C-terminal Myc-epitope tag was introduced immediately preceding the translational stop codon as well as a floxed IRES-lacZ-geo cassette in the 3' UTR.
  • mutations:
  • Insertion
  • synonyms:
  • p110alpha<lz>,
  • p110alpha<lz>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele