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Allele : Efhc1<tm1Kzy> EF-hand domain (C-terminal) containing 1; targeted mutation 1, Kazuhiro Yamakawa

Primary Identifier  MGI:3774032 Allele Type  Targeted
Attribute String  Null/knockout Gene  Efhc1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A pgk-neo cassette was inserted into exon 1 resulting in a frameshift at amino acid 14 and a premature stop codon 6 amino acids downstream of the frameshift. RT-PCR confirmed the absence of RNA expression in the brain, liver, and kidney of homozygous mice. Western blot and immunohistochemical analysis confirmed the absence of protein expression in homozygous mice.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele