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Publication : Expression pattern of Popdc2 during mouse embryogenesis and in the adult.

First Author  Froese A Year  2008
Journal  Dev Dyn Volume  237
Issue  3 Pages  780-7
PubMed ID  18189275 Mgi Jnum  J:131297
Mgi Id  MGI:3773469 Doi  10.1002/dvdy.21431
Citation  Froese A, et al. (2008) Expression pattern of Popdc2 during mouse embryogenesis and in the adult. Dev Dyn 237(3):780-7
abstractText  The Popdc2 gene is a member of the Popeye domain containing gene family encoding membrane proteins with prominent expression in striated and smooth muscle tissue. After introducing a LacZ reporter gene into the Popdc2 locus, expression was studied during embryonic development and postnatal life. At embryonic day (E) 7.5, expression was present in cardiac and extraembryonic mesoderm. At E10.5, expression was found in heart, somites, and mesothelial cells lining the coelom. At E12.5, expression was present in the coelomic mesothelium, pericardial and myocardial layer of the heart, skeletal muscle, bladder, gut, and umbilical vessels. Postnatal expression was found in cardiac and skeletal muscle and in the smooth muscle layer of colon, rectum, and bladder. In the stomach, Popdc2 was exclusively present in the pyloric epithelium. In conclusion, Popdc2 is expressed in various muscle and nonmuscle cell types during embryonic development and in postnatal life. Developmental Dynamics 237:780-787, 2008. (c) 2008 Wiley-Liss, Inc.
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