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Allele : Gt(ROSA)26Sor<tm1Uzs> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ursula Zimber-Strobl
Primary Identifier  MGI:3776037 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence, No functional change Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  BALB/c
Is Recombinase  false Is Wild Type  false
molecularNote  cDNA encoding the first 214 amino acids of Cd40 were fused to the cDNA encoding the Epstein-Barr latent membrane protein 1 (LMP1) and inserted into a modified ROSA locus that contained a floxed stop, non-expressing RFP and frt-flanked neo cassette. The fusion protein is only expressed following cre-mediated recombination to remove the stop cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Gt(ROSA)26Sor<tm1(CD40/Lmp1)Uzs>,
  • Gt(ROSA)26Sor<tm1(CD40/Lmp1)Uzs>,
  • CD40/LMP1<flSTOP>,
  • CD40/LMP1<flSTOP>
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1 Feature

Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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